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| Aflevering | Eerste uitzending |
|---|---|
| S18E01 - Who Smarted? | 19/04/2021 |
| S18E02 - Russian Doll | 26/04/2021 |
| S18E03 - Stan Moves to Chicago | 03/05/2021 |
| S18E04 - Shakedown Steve | 10/05/2021 |
| S18E05 - Klaus and Rogu in Thank God for Loose Rocks: An American Dad! Adventure | 17/05/2021 |
| S18E06 - The Wondercabinet | 24/05/2021 |
| S18E07 - Little Bonnie Ramirez | 31/05/2021 |
| S18E08 - Dancin' A-With My Cells | 07/06/2021 |
| S18E09 - Mused and Abused | 14/06/2021 |
| S18E10 - Henderson | 21/06/2021 |
| S18E11 - Hot Scoomp | 28/06/2021 |
| S18E12 - Lumberjerk | 05/07/2021 |
| S18E13 - Stan & Francine & Stan & Francine & Radika | 12/07/2021 |
| S18E14 - Flush After Reading | 19/07/2021 |
| S18E15 - Comb Over: A Hair Piece | 26/07/2021 |
| S18E16 - Plot Heavy | 02/08/2021 |
| S18E17 - The Sinister Fate!! | 09/08/2021 |
| S18E18 - Dr. Sunderson's SunSuckers | 16/08/2021 |
| S18E19 - Family Time | 23/08/2021 |
| S18E20 - Cry Baby | 30/08/2021 |
| S18E21 - Crystal Clear | 06/09/2021 |
| S18E22 - Steve's Franken Out | 25/10/2021 |