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| Aflevering | Eerste uitzending |
|---|---|
| S48E01 - Secrets in Our DNA | 13/01/2021 |
| S48E02 - Looking for Life on Mars | 24/02/2021 |
| S48E03 - Picture a Scientist | 14/04/2021 |
| S48E04 - Reef Rescue | 21/04/2021 |
| S48E05 - Fighting for Fertility | 12/05/2021 |
| S48E06 - Hindenburg: The New Evidence | 19/05/2021 |
| S48E07 - Great Electric Airplane Race | 26/05/2021 |
| S48E08 - Ship That Changed the World | 02/06/2021 |
| S48E09 - Bat Superpowers | 15/09/2021 |
| S48E10 - The Cannabis Question | 29/09/2021 |
| S48E11 - Particles Unknown | 06/10/2021 |
| S48E12 - Arctic Drift | 13/10/2021 |
| S48E13 - Edible Insects | 20/10/2021 |
| S48E14 - NOVA Universe Revealed: Age of Stars | 27/10/2021 |
| S48E15 - NOVA Universe Revealed: Milky Way | 03/11/2021 |
| S48E16 - NOVA Universe Revealed: Alien Worlds | 10/11/2021 |
| S48E17 - NOVA Universe Revealed: Black Holes | 17/11/2021 |
| S48E18 - NOVA Universe Revealed: Big Bang | 24/11/2021 |
| S48E19 - High-Risk High-Rise | 05/01/2022 |
| S48E20 - Butterfly Blueprints | 12/01/2022 |
| S48E21 - Alaskan Dinosaurs | 19/01/2022 |
| S48E22 - Ancient Maya Metropolis | 26/01/2022 |